Prof. Dr.

Tilo Kircher

Philipps Universität Marburg UKGM
Rudolf-Bultmann Str. 8
35039 Marburg

+49 (0)6421 58 66 218 E-Mail senden Website besuchen

Kurzinfo

Ziel unserer Arbeitsgruppe es, unter Einbeziehung des subjektiven Erlebens, die Funktionsweise des Gehirns und seiner Erkrankungen zu verstehen. Die Ätiologie und Pathogenese von psychischen Störungen untersuchen wir durch Verknüpfung verschiedener Untersuchungsebenen wie Hirnstuktur (strukturelles MRT), Hirnfunktion (fMRT, EEG), Experimentalpsychologie, Neuropsychologie, Psychopathologie und Verlaufsuntersuchungen sowie Genetik und Molekular-/Zellbiologie (in Kooperationen). Ein Fokus sind kognitive und neurowissenschaftliche Erklärungsmodelle für psychiatrische Symptome wie Halluzinationen und Ich-Störungen. Wir gehen davon aus, dass Störungen der Efferenzkopie und Forwärtsmechanismen diesen zugrunde liegen.

Projektrelevante Veröffentlichungen
Arikan, B. E., van Kemenade, B. M., Podranski, K., Steinsträter, O., Straube, B., & Kircher, T. (2019). Perceiving your hand moving: BOLD suppression in sensory cortices and the role of the cerebellum in the detection of feedback delays. Journal of Vision. find paper
He, Y., Steines, M., Sommer, J., Gebhardt, H., Nagels, A., Sammer, G., Kircher, T., Straube, B. (2018). Spatial - temporal dynamics of gesture - speech integration : a simultaneous EEG-fMRI study. Brain Structure and Function, 223(7), 3073-3089. find paper
Krala, M., van Kemenade, B., Straube, B., Kircher, T., & Bremmer, F. (2019). Predictive coding in a multisensory path integration task: An fMRI study. Journal of Vision, 19(11), 13-13. find paper
Pazen, M., Uhlmann, L., van Kemenade, B. M., Steinsträter, O., Straube, B., & Kircher, T. (2020). Predictive perception of self-generated movements: Commonalities and differences in the neural processing of tool and hand actions. NeuroImage, 206, 116309. find paper DOI
Schmitter, C., Steinsträter, O., Kircher, T., van Kemenade, B. M., & Straube, B. (2021). Commonalities and differences in predictive neural processing of discrete vs continuous action feedback. NeuroImage, 117745. find paper.
Straube, B., van Kemenade, B.M., Kircher, T. & Schülke, R. (2020). Transcranial Direct Current Stimulation Improves Action-Outcome Monitoring in Schizophrenia Spectrum Disorder. Brain Communications, 2(2), fcaa151. find paper
Uhlmann, L., Pazen, M., van Kemenade, B. M., Steisträter, O., Harris, L.R., Kircher, T. & Straube, B (2020). Seeing your own or someone else's hand moving in accordance with your action: The neural interaction of agency and hand identity. Human Brain Mapping, 41, 2474-2489. find paper
Uhlmann, L., Pazen, M., van Kemenade, B.M., Kircher, T. & Straube, B. (2021). Neural correlates of self-other distinction in patients with schizophrenia spectrum disorders: The roles of agency and hand identity. Schizophrenia Bulletin. find paper
Van Kemenade, B.M., Arikan, B.E., Podranski, K., Steinsträter, O., Kircher, T., & Straube, B. (2018). Distinct roles for the cerebellum, angular gyrus and middle temporal gyrus in action-feedback monitoring. Cerebral Cortex find paper DOI
Ältere projektrelevante Veröffentlichungen
Arikan , B.E., van Kemenade , B.M., Straube, B., Harris, L.H., & Kircher , T. (2017). Voluntary and Involuntary Movements Widen the Window of Subjective Simultaneity. i-Perception, 8(4), 2041669517719297. DOI find paper
Backasch, B., Sommer, J., Klöhn-Saghatolislam, F., Müller, M.J., Kircher, T.T., & Leube, D.T. (2014). Dysconnectivity of the inferior frontal gyrus: Implications for an impaired self-other distinction in patients with schizophrenia. Psychiatry Research, 223:202-209. find paper
Blos, J., Chatterjee, A., Kircher, T., & Straube, B. (2012). Neural correlates of causality judgment in physical and social context – the reversed effects of space and time. NeuroImage, 63(2), 882-93.
Dowiasch, S., Backasch, B., Einhauser, W., Leube, D., Kircher, T., & Bremmer, F. (2016). Eye movements of patients with schizophrenia in a natural environment. European archives of psychiatry and clinical neuroscience, 266, 43-54. find paper
Green, A., Straube, B., Weis, S., Jansen, A., Willmes, K., Konrad, K., & Kircher, T. (2009). Neural integration of iconic and unrelated coverbal gestures: a functional MRI study. Human Brain Mapping, 30(10), 3309–3324.
He, Y., Gebhardt, H., Steines, M., Sammer, G., Kircher, T., Nagels, A., & Straube, B. (2015). The EEG and fMRI signatures of neural integration: An investigation of meaningful gestures and corresponding speech. Neuropsychologia, 72, 27-42.DOI find paper
Kircher T, Arolt V, Jansen A, Pyka M, Reinhardt I, Kellermann T, Konrad C, Lueken U, Gloster AT, Gerlach AL, Ströhle A, Wittmann A, Pfleiderer B, Wittchen HU, Straube B (2013). Effect of cognitive-behavioral therapy on neural correlates of fear conditioning in panic disorder. Biol Psychiatry, 73(1):93-101.
Kircher TTJ, Rapp A, Grodd W, Buchkremer G, Weiskopf N, Lutzenberger W, Ackermann H, Mathiak K. (2004). Mismatch responses in schizophrenia: a combined fMRI and whole-head MEG study. American Journal of Psychiatry, 161:294-304.
Knoblich G., Stottmeister F., Kircher T. (2004). Self-monitoring in patients with schizophrenia. Psychol Med., 34, 1561-9.
Knoblich, G., & Kircher, T. (2004). Deceiving Oneself About Being in Control: Conscious Detection of Changes in Visuomotor Coupling. Journal of Experimental Psychology: Human Perception and Performance, 30(4), 657–666.
Leube D.T., Knoblich G., Erb M., Grodd W., Bartels M., Kircher T.T. (2003b). The neural correlates of perceiving one's own movements. Neuroimage, 20, 2084- 90.
Leube D.T., Knoblich G., Erb M., Kircher T.T. (2003a). Observing one's hand become anarchic: an fMRI study of action identification. Conscious Cogn, 12, 597-608.
Leube DT, Knoblich G, Erb M, Schlotterbeck P, Kircher T (2010). The neural basis of disturbed efference copy mechanism in patients with schizophrenia. Cognitive Neuroscience, 1, 111-117.
Lindner A., Thier P., Kircher T.T., Haarmeier T., Leube D.T. (2005). Disorders of agency in schizophrenia correlate with an inability to compensate for the sensory consequences of actions. Curr Biol., 15, 1119-24.
Mainieri A.G., Heim S., Straube B., Binkofski F., Kircher T. (2013). Differential Role of Mentalizing and the Mirror Neuron System in the Imitation of Communicative Gestures. NeuroImage, 81, 294–305.
Nagels, A., Kircher, T., Steines, M., Grosvald, M., & Straube, B. (2015). A brief self-rating scale for the assessment of individual differences in gesture perception and production. Learning and Individual Differences, 39, 73–80. DOI find paper
Schmalenbach, S.B., Billino, J., Kircher, T., van Kemenade, B.M., & Straube, B. (2017). Links between gestures and multisensory processing: individual differences suggest a compensation mechanism. Frontiers in Psychology, 8:1828 find paper DOI
Straube B, Green A, Jansen A, Chatterjee A, Kircher T. (2010). Social cues, mentalizing and the neural processing of speech accompanied by gestures. Neuropsychologia, 48:382-393.
Straube B, Green A, Sass K, Kirner-Veselinovic A, Kircher T. (2013). Neural integration of speech and gesture in schizophrenia: Evidence for differential processing of metaphoric gestures. Human Brain Mapping, 34(7), 1696–1712.
Straube, B., Green, A., Bromberger, B. & Kircher, T. (2011). The differentiation of iconic and metaphoric gestures: Common and unique integration processes. Human Brain Mapping, 32, 520-533.
Straube, B., Green, A., Chatterjee, A. & Kircher, T. (2011). Encoding social interactions: The neural correlates of true and false memories. Journal of Cognitive Neuroscience, 23, 306- 24.
Straube, B., Green, A., Sass, K., & Kircher, T. (2014). Superior Temporal Sulcus Disconnectivity During Processing of Metaphoric Gestures in Schizophrenia. Schizophrenia Bulletin, 40(4), 936?944. DOI find paper
Straube, B., Green, A., Sass, K., Kirner-Veselinovic, A. & Kircher, T. (2013). Neural integration of speech and gesture in schizophrenia: Evidence for differential processing of metaphoric gestures. Human Brain Mapping, 34(7), 1696–1712.
Straube, B., Green, A., Weis, S., & Kircher, T. (2012). A Supramodal Neural Network for Speech and Gesture Semantics: An fMRI Study. PLoS ONE, 7(11), e51207. doi:10.1371/journal.pone.0051207.
Straube, B., He, Y., Steines, M., Gebhardt, H., Kircher, T., Sammer, G., & Nagels, A. (2013). Supramodal neural processing of abstract information conveyed by speech and gesture. Frontiers in Behavioral Neuroscience, 7. doi:10.3389/fnbeh.2013.00120
Straube, B., van Kemenade, B. M., Arikan, B. E., Fiehler, K., Harris, L. R., Leube, D., & Kircher, T. (2017). Predicting the multisensory consequences of one's own action: BOLD suppression in auditory and visual cortices. PLOS ONE, 12(1), e0169131. DOI find paper
Van Kemenade, B. M., Kircher, T., Arikan, B. E., & Straube, B. (2016). Predicting the sensory consequences of one’s own action: First evidence for multisensory facilitation. Attention, Perception, & Psychophysics, 78(8), 2515-2526. DOI find paper
van Kemenade, B.M., Arikan, B.E., Kircher, T., & Straube, B. (2017). The angular gyrus is a supramodal comparator area in action-outcome monitoring. Brain Structure and Function, 1-13. DOI find paper
Wende, K. C., Nagels, A., Stratmann, M., Chatterjee, A., Kircher, T., & Straube, B. (2015). Neural basis of altered physical and social causality judgements in schizophrenia. Schizophrenia Research, 161(2–3), 244–251. find paper
Whitney C, Grossmann, Kircher T. (2009). The influence of multiple primes on bottom-up and topdown regulation during meaning retrieval: evidence for two distinct neural networks. Cerebral Cortex, 19:2548-2560.